Our study Molecular dynamics and intracellular signaling of the TNF-R1 with the R92Q mutation has been accepted for publication in the Journal of Neuroimmunology. This work was started at the Centre d’Esclerosi Múltiple de Catalunya (Cemcat) and is a continuation of the previous paper TNFRSF1A polymorphisms rs1800693 and rs4149584 in patients with multiple sclerosis. Permanent link to this publication: Link.
Communication sent to the fourth workshop on New Trends of Computational Chemistry for Industry Applications organized by the Catalonian Reference Network on Theoretical and Computational Chemistry (XRQTC), 1-2 October, 2015:
The Spanish Supercomputing Network (RES), coordinated by the Barcelona Supercomputing Center (BSC), and the High Performace Computing Advisory Council, will held the 4th HPC Advisory Council Spain Conference and the 9th RES Users’Conference on 22nd & 23rd September 2015, in Barcelona (Spain).
Poster: Computational exploration of the binding mode of the heme-dependent activator YC-1 into the active catalytic domain of soluble guanylate cyclase
Presenter: Luis Agulló, Universitat de Vic – Universitat Central de Catalunya.
The student Gemma Obiol (Biotechnology, UVic) will perform an externship in our laboratory. She will work on the project Modulation of guanylate cyclases.
Our communication to the 7th International Conference on cGMP received the Poster Award cGMP 2015 and was selected for oral presentation:
Agulló L, Buch I, de Terán H, de Fabritis G, Garcia-Dorado D, Villà-Freixa J. Computational exploration of the binding mode of the heme-dependent activator YC-1 into the active catalytic site of soluble guanylate cyclase. BMC Pharmacology and Toxicology 2015, 16(Suppl 1):A32 (2 September 2015)
7th International Conference on cGMP Generators, Effectors and Therapeutic Implications. Trier, Germany, 19-21 June 2015.
UVic-UCC International Workshop on Higher Education (section: Workshop on Biomedical Data Integration and Modeling in Translational Research), 9-12 June, 2015:
Link to this particular section of the International Workshop.
The study on the effect of stretch-activated channel blocker GsMtx4 (a peptide toxin from Grammostola spatulata spider venom) the on arrhythmias after coronary occlusion has been accepted in PlosOne:
Barrabés JA, Inserte J, Agulló L, Rodríguez-Sinovas A, Alburquerque-Béjar JJ, Garcia-Dorado D. Effects of the Selective Stretch-Activated Channel Blocker GsMtx4 on Stretch-Induced Changes in Refractoriness in Isolated Rat Hearts and on Ventricular Premature Beats and Arrhythmias after Coronary Occlusion in Swine. PLoS One. 2015 May 4;10(5):e0125753.
Communication sent to the conference: Computing free energy across disciplines:from method development to applications, that has taken place on Münster (Germany), March 9-11, 2015.
Poster: Agulló L, Buch I, de Terán H, de Fabritis G, Garcia-Dorado D, Villà-Freixa J. Binding of the heme-dependent activator YC-1 into the active catalytic site of soluble guanylate cyclase.
Martin Floor, a doctoral student of the University of Chile will stay in our lab for several months.
Publicat dins de Laboratory
II Jornada de Bioinformàtica i Biologia Computacional Organitzada per la Secció de Bioinformàtica i Biologia Computacional de la SCB i Bioinformatics Barcelona. INSTITUT D´ESTUDIS CATALANS Sala Prat de la Riba, Institut d’Estudis Catalans Carrer del Carme, 47. Barcelona. Carrer del Carme 47, Barcelona. 12 de desembre de 2014.
MODULATION OF THE IMMUNE RECEPTORS CD300F AND CD200R AS A NOVEL THERAPEUTIC STRATEGY FOR ACUTE CNS DAMAGE. Luis Agulló and Jordi Villà-Freixa. Research Group in Bioinformatics and Medical Statistics (BEM), Polytechnic School, University of Vic – Central University of Catalonia, 08500 Vic.